Total phenolic and flavonoids content, and in vitro antioxidant and antimicrobial activity of ethyl acetate and butanol extract from Senecio delphinifolius Vahl.

Der Pharmacia Lettre

Yasmine Arab¹ 

关键词: Yasmine Arab;    Amar Zellagui;    Saber Boutellaa;    Khaled Mesbah;    Noureddine Gherraf;    Senecio delphinifoliusVahl.;    phenolic;    flavonoids content;    antioxidant;    antimicrobial activity;   

DOI  :  

学科分类：药理学

来源: Scholars Research Library

【 摘 要 】

The present work focuses essentially on the total phenolic and flavonoidscontents, and in vitro antioxidant and antimicrobial activity of two fractions: ethyl acetate and n-butanol extracts of an Algerian endemic plant: Senecio delphinifolius. The total phenolic content was determined using Folin-ciocalteu reagent to yield 7.22 ± 0.84 and 7.86 ± 0.25mg GA/mg respectively. The flavonoids contents were 22.96± 1.41 and 10.25 ± 8.94 mg Q/mg respectively. Antioxidant activity was performed using DPPH reagent. Antioxidant activity ranged from 80.48 % to 73.91 %, using ascorbic acid as a control test. The antimicrobial activity of the two extracts was investigated using a diffusion method against most common pathogenic bacterial strains: E. coli ATCC 2592, Pseudomonas aerogenosa ATCC2783, Staphylococcus aureus ATCC 252923, Selmonella sp., Klebseilla pneumonia and one fungus Candida albicans. The finding show that this extracts have a strong antioxidant activity and can be used as a natural source of scavenging agents.

【 授权许可】

CC BY