Active-site solvent replenishment observed during human carbonic anhydrase II catalysis

IUCrJ

Mahon, B.P.¹  McKenna, R.¹  Lomelino, C.L.¹  Avvaru, B.S.¹  Kim, C.U.²  Kim, J.K.²  Park, S.³ 

[1] Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA;Department of Physics, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea;School of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea

关键词: CARBONIC ANHYDRASE II;    PROTON TRANSFER;    WATER DYNAMICS;    HIGH-PRESSURE CRYOCOOLING;    ACTIVE-SITE SOLVENT REPLENISHMENT;   

DOI  :  10.1107/S2052252517017626

学科分类：数学（综合）

来源: International Union of Crystallography

【 授权许可】

CC BY