Graphene Based Composite Hydrogel for Biomedical Applications

Croatica Chemica Acta

Rhee, Kyong Yop¹  Abudabbus, Mohamed M.²  Nešović, Katarina²  Mišković-Stanković, Vesna² 

[1] Department of Mechanical Engineering, Kyung Hee University, 17104 Yongin, South Korea;University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia

关键词: hydrogels;    silver nanoparticles;    poly(vinyl alcohol);    graphene;    nanocomposites;    electrochemical synthesis;   

DOI  :  10.5562/cca3133

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV–vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene-based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.

【 授权许可】

CC BY