Sympathetic Nerve Entrapment Point Injection as an Antireflux Procedure for Refractory Laryngopharyngeal Reflux: A First Case Report of Innovative Autonomic Regulation

Innovations in Clinical Neuroscience

Sangsoo Lee,MD,MSc ; Chang Jin Oh,MD ; and Jeong Won Seong,MD

关键词: Sympathetic nerve entrapment point injection, antireflux procedure, refractory, laryngopharyngeal reflux, reflux, autonomic regulation;   

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Surgical treatment is not suitable for laryngopharyngeal reflux that is refractory to proton pump inhibitors. We present a case of proton pump inhibitor-refractory laryngopharyngeal reflux that was successfully treated with sympathetic nerve entrapment point injection. The patient had previously been diagnosed with laryngopharyngeal reflux and treated with proton pump inhibitors for six months without substantial improvement. After sympathetic nerve entrapment point injection treatment, her reflux symptom index improved from 15 points to 1 point, and this response was maintained for six months. Hyperexcitability of T5 and T6 sympathetic preganglionic fibers appears to be the main cause of laryngopharyngeal reflux. Sympathetic nerve entrapment point injection may represent an alternative to anti-reflux procedures.

【 授权许可】

Unknown