Effects of organochlorines on cytochrome P450 activity and antioxidant enzymes in liver of roundnose grenadier Coryphaenoides rupestris

Aquatic Biology

关键词: Deep-sea fish;    Cytochrome P450;    EROD;    PCBs;    DDTs;    Antioxidant enzymes;   

DOI  :  10.3354/ab00227

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: Oceans function as a sink for organochlorine compounds (OCs) such as PCBs and DDTs. Deep-sea fish bioaccumulate OCs to levels 10 to 100 times higher than shallow-water species. OCs induce the cytochrome P450 (CYP) system, the activity of which may increase reactive oxygen species (ROS) production in liver cells. However, the susceptibility of fish to the oxidative stress likely caused by OCs remains unclear. We analysed whether PCB and DDT contamination of roundnose grenadier

【 授权许可】

CC BY