Pressure effects on lipids and bio-membrane assemblies

IUCrJ

Brooks, N.J.¹ 

[1] Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, England

关键词: BIOLOGICAL MEMBRANES;    LIPIDS;    BILAYERS;    LIPID-PROTEIN ASSEMBLIES;    HIGH-PRESSURE STUDIES;   

DOI  :  10.1107/S2052252514019551

学科分类：数学（综合）

来源: International Union of Crystallography

【 摘 要 】

Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the mesostructure of lipid membranes, bilayer organization and lipid–protein assemblies. It also summarizes recent developments in high-pressure structural instrumentation suitable for experiments on membranes.

【 授权许可】

CC BY