期刊论文详细信息
International Journal of Biomedical and Advance Research | |
SYNTHESIS, ANTI-INFLAMMATORY AND ANTI-MICROBIAL ACTIVITY OF PYRIMIDINE-5-CARBOXYLATE DERIVATIVES | |
A. S. Dongarwar ; B. E. Wanjari ; M. V. Nema ; P. P. Katolkar ; A. O. Turaskar ; T. P. Nimbekar | |
关键词: s Pyrimidine-5-Carboxylate; Aromatic anilines; Guanidines; Benzamidine; Antiinflammatory; Anti-microbial activity; | |
学科分类:药学、药理学、毒理学(综合) | |
来源: Scholar Science Journals | |
【 摘 要 】
Ethyl-2-amino-4-chloro-6-(2, 4, 6 trichloro phenyl amino) pyrimidine-5-carboxylate and ethyl-2-amino 4-chloro-1, 3-dimethyl-6-(phenyl amino)-1,2,3,4 tetrahydro pyrimidine-5- carboxylate derivatives were synthesized through Cyclocondensation and Michel type of addition reaction with the aromatic anilines, guanidine and benzamidines. Synthesized novel derivatives were confirmed by elemental analysis viz., IR, 1HNMR and Mass spectroscopy. These novel derivatives have been screened for Antibacterial, Antifungal and Antiinflammatory activity.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201902185847707ZK.pdf | 141KB | download |