Acta Crystallographica Section E: Crystallographic Communications | |
Hydrogen-bonding patterns in 5-fluorocytosine–melamine co-crystal (4/1) | |
Sanjeewa, L.D.1  McMillen, C.D.1  Mohana, M.2  Muthiah, P.T.2  | |
[1] Department of Chemistry, Clemson University, H. L. Hunter Laboratories, Clemson, SC 29634, USA;School of Chemistry, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India | |
关键词: CRYSTAL STRUCTURE; 5-FLUOROCYTOSINE; MELAMINE; HOMOSYNTHONS; HYDROGEN BONDING; | |
DOI : 10.1107/S205698901600476X | |
学科分类:数学(综合) | |
来源: International Union of Crystallography | |
【 摘 要 】
The asymmetric unit of the title compound, 4C4H4FN3O·C3H6N6, comprises of two independent 5-fluorocytosine (5FC) molecules (A and B) and one half-molecule of melamine (M). The other half of the melamine molecule is generated by a twofold axis. 5FC molecules A and B are linked through two different homosynthons [R22(8) ring motif]; one is formed via a pair of N—H⋯O hydrogen bonds and the second via a pair of N—H⋯N hydrogen bonds. In addition to this pairing, the O atoms of 5FC molecules A and B interact with the N2 amino group on both sides of the melamine molecule, forming a DDAA array of quadruple hydrogen bonds and generating a supramolecular pattern. The 5FC (molecules A and B) and two melamine molecules interact via N—H⋯O, N—H⋯N and N—H⋯O, N—H⋯N, C—H⋯F hydrogen bonds forming R66(24) and R44(15) ring motifs. The crystal structure is further strengthened by C—H⋯F, C—F⋯π and π–π stacking interactions.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201902185123138ZK.pdf | 633KB | download |