Immune-diagnosis of latent toxoplasmosis in childbearing age women in rural areas in EL Geizera State, Sudan

International Journal of Medicine and Medical Sciences

Khalil Mohamed¹  Ali Abdel Magid²  Marek Maly³  Petr Kodym⁴  Intisar EL Rayah⁵  Alia Bilal⁵  EL Taib Gumaa⁵ 

[1] Commission for Biotechnology and Genetic Engineering, Department of Medical Biotechnology, Khartoum, Sudan.;Ministry of Science and Technology, Sudan.;National Institute of Public Health, Department of Biostatistics and Informatics, Prague, Czech Republic.;National Institute of Public Health, National Reference Laboratory for Toxoplasmosis, Prague, Czech Republic.;Tropical Medicine Research Institute TMRI, Khartoum, Sudan.

关键词: Prevalence;    toxoplasma;    childbearing;   

学科分类：医学（综合）

来源: Academic Journals

【 摘 要 】

The  current  study  is  aimed to  evaluate  the  prevalence  rate  of  latent  toxoplasmosis  among childbearing  women  in  rural  areas in EL Geizera State. A total of  255 plasma  samples were collected  from  two  villages;  AL Nuba  and  EL Massoudia  in  EL Geizera  State, Sudan.  and tested for Toxoplasma gondii  antibodies  using three   different  screening  tests (Latex  Agglutination  Test LAT,-Enzyme  Link  Immunosorbent  Assay  IgG, and Complement  Fixation  test  (CFT) and  one standard  technique (Indirect  Immunofluorescent  Test  (IIFT). The overall seroprevalence rate in the two villages was found 73.1%, using the standard method (IIFT). The prevalence rate was 60.7%  in  EL Nuba and  87.3%  in EL Massoudia. The  seroprevalence  rate  were found  to be 62.3,  73.1,  and  72.3% using the other  three  screening  tests  LAT,  ELISA  IgG,  and  CFT  respectively. The prevalence rate  was found   increasing   with  age  (p<0.001). Infection rate was higher in EL Massoudia village (p<0.001). This  study  indicated  that  there  is  a  considerable  rate  of  Toxoplasma  infection  among  rural women  and  supported  the  concern  that  rural  women  in  Sudan  may be   vulnerable  to  that infection.

【 授权许可】

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