Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles

IUCrJ

McKenna, R.¹  Aggarwal, M.¹  Kondeti, B.¹  Maupin, C.M.²  Silverman, D.N.³  Tu, C.³ 

[1] Department of Biochemistry and Molecular Biology, University of Florida, PO Box 100245, Gainesville, FL 32610, USA;Department of Chemical and Biological Engineering, Colorado School of Mines, 1500 Illinois Street, Golden, CO 80401, USA;Department of Pharmacology and Therapeutics, University of Florida, PO Box 100247, Gainesville, FL 32610, USA

关键词: HUMAN CARBONIC ANHYDRASE;    H64A;    ACTIVITY ENHANCEMENT;    RESCUE;    ACTIVATION;    IMIDAZOLE;   

DOI  :  10.1107/S2052252514004096

学科分类：数学（综合）

来源: International Union of Crystallography

【 授权许可】

CC BY