Histopathological study of hepatobiliary malignancies and its correlation with clinical features

International Journal of Biomedical and Advance Research

Ragini Thapa ; K. Pushpalatha Pai

关键词: s Carcinoma, hepatobiliary system;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Objectives: The aim of the study is to analyze hepatobiliary malignant tumors histologically, histochemically, immunohistochemically wherever possible and compare with the clinical features and review the literature. Methods: It is a retrospective clinicopathologic study using routine and special histopathological methods with information from clinical records Results: The age of the patients ranged from 32 to 72 years with male predominance. There were 5 cases of metastatic tumours and 2 cases of primary tumours of liver without cirrhosis both being hepatocellular carcinomas (HCC) where one was fibrolamellar type with amyloid deposition. There were 4 cases of primary and one case of secondaries in the gall bladder with majority associated with cholelithiasis. Extrahepatic biliary system had one case of adenocarcinoma. Conclusions: The liver is the most common site of malignancy of hepatobiliary system where secondaries are dominating followed by gall bladder with the primary being most common. Fibrolamellar type of hepatocellular carcinoma is not uncommon but amyloid in the tumor tissue has not been reported in the literature. Least common site of hepatobiliary system cancer is extra hepatic bile duct.

【 授权许可】

CC BY