Biofilm formation among Candida albicans isolated from vagina

International Journal of Biomedical and Advance Research

D C Thamke ; H A Tayade ; Surekha Tayade ; N. J. Bankar ; N. G. Rathod

关键词: s Candida albicans, Biofilm formation, Vulvovaginal candidiasis;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Purpose: Study was conducted in a rural tertiary care hospital with a purpose to demonstrate the biofilm forming abilities of C. albicans isolated from cases of vulvovaginal candidiasis and asymptomatic carriers. Material and Methods: C. albicans was isolated and identified by standard laboratory techniques. Biofilm formation in vitro was tested using the 96 well microtitre plate method with crystal violet staining. Results: Overall rate of Candida isolation in study subjects was 40%. Candida isolation in cases was 56% and that of controls was 24%. C. albicans was the predominant species in cases and controls (71.45% and 91.67%). Biofilm formation was seen in 40% versus 27.27% in cases and controls. Conclusion: C. albicans isolated from cases and controls demonstrated similar biofilm forming abilities. Other virulence factors may be more significant than biofilm formation in pathogenesis of VVC. Further studies are needed to investigate the issue on larger sample size.

【 授权许可】

CC BY