Nanotechnology for biomedical applications - enhancement of photodynamic activity by nanomaterials

Bulletin of the Polish Academy of Sciences. Technical Sciences

J. Puci?skaInstitute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, PolandOther articles by this author:De Gruyter OnlineGoogle Scholar¹  H. PodbielskaInstitute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, PolandOther articles by this author:De Gruyter OnlineGoogle Scholar¹  K. Wysocka-KrólInstitute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, PolandOther articles by this author:De Gruyter OnlineGoogle Scholar¹  A. Ulatowska-Jar?aInstitute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, PolandOther articles by this author:De Gruyter OnlineGoogle Scholar¹  I. Ho?owaczInstitute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, PolandOther articles by this author:De Gruyter OnlineGoogle Scholar¹ 

[1] Institute of Biomedical Engineering and Instrumentation, Wroc?aw University of Technology, 27 Wybrze?e Wyspia?skiego St., 50-370 Wroc?aw, Poland

关键词: Keywords: silver-doped nanomaterials;    silica-titania (SiO2-TiO2) materials;    photodynamic activity;    fluorescence enhancement;   

DOI  :  10.2478/v10175-011-0031-0

学科分类：工程和技术（综合）

来源: Polska Akademia Nauk * Centrum Upowszechniania Nauki / Polish Academy of Sciences, Center for the Advancement of Science

【 摘 要 】

Over the last two decades nanotechnology has become one of the most dynamically evolving field of research. The unique properties of nanomaterials, not disclosing at microscale, are examined and exploited to extend our understanding of the interactions taking place at atomic or molecular level. Those findings affect research in many areas, like e.g. alternative energy sources, electronics, physics and medicine. In this paper, the possibility of using nanomaterials for the enhancement of photodynamic activity, is discussed. A brief review on drug-delivery facilitating nanomaterials, regarding their characteristic features, is presented. An exemplary application of silver-doped nanomaterials for enhancement of photodynamic properties of two photosensitizers: Photolon and Protoporphyrin IX, is described. Influence of silver-doped nanomaterials addition on the fluorescence intensity of photosensitizers immobilized in silica-titania (SiO2-TiO2) sol was examined via VIS spectroscopy. Influence of sonication on the fluorescence enhancement was also investigated. It was demonstrated that the fluorescence enhancement of photosensitizers depends on the concentration of both: photosensitizer and silver-doped nanoparticles.

【 授权许可】

Unknown