Morphological and neurohistological changes in adolescent rats administered with nicotine during intrauterine life

Nigerian Journal of Physiological Sciences

关键词: Cortex;    Histology;    Prenatal nicotine;    Adolescent rats;    Neurological abnormalities;   

学科分类：内科医学

来源: University of Calabar

【 摘 要 】

Tobacco smoking has been linked to many preventable diseases affecting various organs and systems of the body, including the brain. The current study was conducted to demonstrate the histological changes observable in the cerebral cortex of young Wistar rats exposed to nicotine during gestation. Vaginal smearing was conducted for the female Wistar rats to determine their oestrous cycle, after which they were exposed to male rats overnight, for mating. Pregnancy was confirmed and the pregnant rats were divided into 3 groups based on the 3 trimesters (A, B, C), with each group having a control and a treated subgroup. The Control Groups (A

【 授权许可】

Unknown