ANTIIMPLANTATION ACTIVITY OF THE METHANOLIC EXTRACT OF CORDIA DICHOTOMA LAM. BARK IN RATS

International Journal of Biomedical and Advance Research

Parimal P. Katolkar ; Bhumesh. E. Wanjari ; Tulsidas. P. Nimbekar ; Nandkishor J. Duragkar

关键词: s Cordia dichotomy;    antiimplantation activity;    antifertility activity;    methanolic extract.;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

In the present study, antiimplantation activity of methanolic extract of Cordia dichotoma Lam. bark was evaluated. The methanolic extract of bark of Cordia dichotoma showed significant antiimplantation activity. Pretreatment with methanolic extract showed significant inhibition of number of implant site at a dose of 100-mg/kg-body weight. There was no change in ovulation; hence the antiimplantation activity observed in the present study with Cordia dichotoma bark can be attributed largely to its inhibition of number of implants. However, an investigation of  the antiimplantation activity showed  no increase in body weight or uterine content of blood glucose, cholesterol and triglyceride levels when compared with control group.

【 授权许可】

CC BY