A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model

IUCrJ

Araç, D.¹  Pannu, N.S.¹  Skubák, P.²  Larsen, S.³  Salzman, G.³  Mueller-Dieckmann, C.⁴  Hoelz, A.⁵  Correia, A.R.⁵  Bowler, M.W.⁶  McCarthy, A.A.⁶  Otten, H.⁷  Leonard, G.A.⁷  McSweeney, S.⁷ 

[1] Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA;Department of Biophysical Structural Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands;Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark;Department of Photon Sciences, Brookhaven National Laboratory, Upton, NY 11973-5000, USA;Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA;European Molecular Biology Laboratory, Grenoble Outstation, 71 Avenue des Martyrs, 38000 Grenoble, France;European Synchrotron Radiation Facility, 71 Avenue des Martyrs, CS 40220, 38043 Grenoble, France

关键词: LOW RESOLUTION;    X-RAY CRYSTALLOGRAPHY;    SINGLE-WAVELENGTH ANOMALOUS DIFFRACTION;    MULTIVARIATE STATISTICS;    MODEL BIAS;    STRUCTURE DETERMINATION;    MEMBRANE PROTEINS;    REFINEMENT;    MULTI-PROTEIN COMPLEXES;   

DOI  :  10.1107/S2052252517017961

学科分类：数学（综合）

来源: International Union of Crystallography

【 授权许可】

CC BY