Identifying an important change estimate for the Multiple Sclerosis Walking Scale-12 (MSWS-12v1) for interpreting clinical trial results:

Multiple Sclerosis Journal – Experimental, Translational and Clinical

Lahar Mehta¹  Jacob Elkins¹  John Zhong¹  Manjit McNeill²  Jiat-Ling Poon³  Kathleen W Wyrwich³  Priscilla Auguste³  Jeremy Hobart⁴ 

[1] Biogen, Cambridge, MA, USA;Biogen, Maidenhead, UK;Evidera, Inc., Bethesda, MD, USA;Peninsula Schools of Medicine and Dentistry, Plymouth University, Plymouth, UK

关键词: Important change;    meaningful improvement;    responder definition;    MSWS-12;    patient-reported outcome;    multiple sclerosis;    walking ability;    anchor-based analysis;    distribution-based analysis;   

DOI  :  10.1177/2055217315596993

学科分类：医学（综合）

来源: Sage Journals

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