Anti-inflammatory activity of Salvia officinalis L.

Dynamic Chiropractic

Renata Grespan¹  Thiago Oliveira Farinha¹  Rilson Jose do Pinho²  Expedito Leite da Silva²  Jefferson Pitelli Fonseca³  o⁴  Marcio Jose Damiatilde⁵  Gessilda Alcantara Nogueira de Melo⁶ 

[1] –PR, Brazil.;, CEP 87020-900 Maringá, MaringáDepartment of Chemistry, State University of MaringáDepartment of Pharmacology and Therapeutics, State University of Maringá

关键词: Salvia officinalis;    essential oil;    anti-inflammatory;    medicinal plants.;   

DOI  :  10.5897/JMPR12.251

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

This study evaluate the effects of sage hydroalcoholic extract (SE) and sage essential oil (SO) on the inflammatory response using an experimental model of acute inflammation and a leukocyte migration assay. In the carrageenan-induced pleurisy test, SE did not reduce the exudate volume and leukocyte migration to the pleura, but SE exerted a topical anti-inflammatory effect by significantly inhibiting croton oil-induced ear edema. All SO doses tested significantly inhibited leukocyte chemotaxis induced by casein and reduced the number of rolling, adhesion, and leukocytes migration to spermatic fascia after inflammatory stimulus. Our data demonstrated that SO has anti-inflammatory activity.

【 授权许可】

Unknown