Assaying the variation in secondary metabolites of St. Johns wort for its better use as an antibiotic

Dynamic Chiropractic

Sasa Z. Zlatkovic¹  Goran S. Nikolic² 

[1] Actavis Trading Ltd, Djordja Stanojevica 12, Novi Beograd 11070, Serbia.;Faculty of Technology, Bulevar oslobodjenja 124, Leskovac 16000, Serbia.

关键词: Imanin;    St. John’    s wort;    antimicrobial activity;    hyperforin;    plant vegetation.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The present study is aimed at investigating the effects of variation in secondary metabolites of St. John’s wort for its better use as an antibiotic. Theseasonal dynamicsinvestigationof St. John’s wort secondary metabolites was carried out on annual, biennial and triennial wild-growing plants of the suburban localities, and on the indigenous perennial plants of the mountainous localities. The effects of variation in secondary metabolites of the plant material were monitored using a complex antimicrobial preparation imanin. As plantsecondary metabolites, imanin was isolated fromflowers and leaves ofSt. John’s wort by aqueous-alkaline extraction. The quality of imanin contained inSt. John’s wortwas determined by FTIR and HPLC methods.The imanin extracts were tested for antimicrobial activity againstStaphylococcus aureus,Streptococcus agalactiae,Bacillus diphteriae,Bacillustetani,Clostridium histolyticus,BacillusmesentericusandBacillus mycoides.The quantitative effects of temperature and light intensity on imanin accumulations in St. John’s wort were examined depending on the sampling periods and location. The results of antimicrobial activity and quantitative effects of climatic conditions were correlated with vegetation phases of hypericum plants.

【 授权许可】

Unknown