Chemical composition and evaluation of acetylcholinesterase inhibition and antioxidant activity of essential oil from Dalmatian endemic species Pinus nigra Arnold ssp. dalmatica (Vis.) Franco

Dynamic Chiropractic

关键词: Acetylcholinesterase inhibition;    antioxidant activity;    essential oil;    Pinus nigrassp.dalmatica;    endemic species.;   

DOI  :  10.5897/JMPR10.289

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

In the present study, the chemical composition and biological activity (acetylcholinesterase inhibition and antioxidant activity) of essential oil from endemic speciesPinus nigraArnold ssp.dalmatica(Vis.) Franco was investigated.α-Pinene,β-pinene, germacrene D and ß-caryophyllene were identified by GC-FID and GC-MS as dominant components of the oil.P. nigrassp.dalmaticaessential oil showed relatively high inhibitory activity on acetylcholinesterase (AChE), which can be in relation with good AChE inhibitory activity of pure main monoterpene components of the oil (S-a-pinene) and their mixtures (S‑a-pinene:S-ß-pinene andR-a-pinene:S-ß-pinene, in ratio 3:2). Essential oil fromP. nigrassp.dalmaticadid not show significant antioxidant activity tested by three methods: DPPH radical scavenging method, Ferric Reducing Antioxidant Potential (FRAP) and Thiobarbituric Acid Reactive Species (TBARS) assays.

【 授权许可】

Unknown