Repellence effectiveness of essential oils from some Tanzanian Ocimum and Hyptis plant species against afro-tropical vectors of malaria and lymphatic filariasis

Dynamic Chiropractic

Calista Imeda¹  Hamisi M. Malebo²  Shaaban J. Katani³  Nteghenjwa A. Kitufe⁴  Richard Sunguruma⁵ 

[1] Amani Medical Research Centre, National Institute for Medical Research, P. O. Box 81, Muheza, Tanzania.;Department of Traditional Medicine Research, National Institute for Medical Research, P. O. Box 9653, Dar es Salaam, Tanzania.;Government Chemist Laboratory Agency, P. O. Box 164, Dar es Salaam, Tanzania.;Ministry of Health and Social Welfare, P. O. Box 9083, Dar es Salaam, Tanzania.;RTI International, Centre for Strategic Malaria Solutions, Global Health Group, P. O. Box 1181-00621, Nairobi, Kenya.

关键词: Repellent plants;    Labiatae;    Anopheles gambiae;    Culex quinquefasciatus;    essential oils.;   

DOI  :  10.5897/JMPR11.732

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Essential oils from three plant species growing in Dar es Salaam, Tanzania,Ocimum gratissimum(OG),Ocimum tenuiflorum(OT) andHyptis suaveolens(HS)all from family Labiateae, were extracted by hydrodistillation and evaluated for laboratory and field based repellency against afro-tropical vectors of malaria and lymphatic filariasis. All oils were found to exhibit high mosquito repellency activity againstAnopheles gambiaesensu stricto in the laboratory tests with RC50values ranging from 2.0- to 15-×10−5mg cm−2, whereas standardN,N-diethyl- 3-toluamide (DEET) was more repelling with RC50value of 0.1×10−5mg cm−2. The formulation containing 10% ofO. gratissimumprovided protection against mosquito bites fromAnopheles funestusof 70.5 to 95.7%,A. gambiaeof 63.2 to 91.5% andCulex quinquefasciatusof 83.8 to 89.5%. The 30%O. gratissimumformulation was more effective with better protection against mosquito bites fromA. funestusof 84.2 to 96.6%,A. gambiaeof 73.7 to 91.5% andC. quinquefasciatusof 89.5 to 91.5%. The formulation containing 15% DEET showed slightly lower protection against mosquito bites fromA. funestusof 70.5 to 78.9%,A. gambiaeof 68.4 to 94.0%,C. quinquefasciatusof 85.5 to 89.5% (P<0.05). The individual components of the oils were identified by GC-MS. The implication of these results in the development and promotion of repellent plant extracts for commercialization is of priority in rural Tanzania where whole plants are currently used as repellents against mosquito vectors.

【 授权许可】

Unknown