Chemical composition and biological activities of a new essential oil chemotype of Tunisian Artemisia herba alba Asso

Dynamic Chiropractic

Nacim Zouari³  Sami Zouari⁵  M. A. Ayadi⁶  Ali Bougatef⁸  Nahed Fakhfakh⁹  Mohamed Neffati^1,10 

[1] ) 3038, Sfax, Tunisia.;Analyse Alimentaire, (ENIS), BP (1173) 3038, Sfax, Tunisia.;Ecologie Pastorale, Institut des RéIngéLaboratoire d’Laboratoire de Biochimie et de GéLaboratoire de Gédenine-Tunisia.;gions Arides, 4119 Ménie Enzymatique des Lipases, Ecole Nationale d’nie Enzymatique et de Microbiologie, (ENIS), BP (1173) 3038, Sfax, Tunisia.;nieurs de Sfax (ENIS), BP (1173 

关键词: Artemisia herba alba;    essential oil;    chemical composition;    antioxidant activity;    angiotensin I-converting enzyme inhibitory;    antimicrobial activity.;   

DOI  :  10.5897/JMPR09.506

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The aim of the present study was to investigate the chemical composition,antioxidant,angiotensin I-converting enzyme (ACE)inhibitory,antibacterial and antifungalactivities of the essential oil ofArtemisia herba albaAsso (Aha), a traditional medicinal plant widely growing in Tunisia. The essential oil from the air dried leaves and flowers ofAhawere extracted by hydrodistillation and analyzed by GC and GC/MS. More than fifty compounds, out of which 48 were identified. The main chemical class of the oil was represented by oxygenated monoterpenes (50.53%). These were represented by 21 derivatives, among which thecis-chrysantenyl acetate (10.60%), the sabinyl acetate (9.13%) and the α-thujone (8.73%) were the principal compounds. Oxygenated sesquiterpenes, particularly arbusculones were identified in the essential oil at relatively high rates. TheAha essential oil was found to have an interesting antioxidant activity as evaluated by the2,2-diphenyl-1-picrylhydrazyl andtheβ-carotene bleaching methods. TheAha essential oil also exhibited an inhibitory activity towards theACE. The antimicrobial activities ofAhaessential oil was evaluated against six bacterial strains and three fungal strains by the agar diffusion method and by determining the inhibition zone. The inhibition zones were in the range of 8-51 mm. The essential oil exhibited a stronggrowth inhibitory activity on allthestudied fungi. Our findings demonstrated thatAhagrowing wild inSouth-Western of Tunisia seems to be a new chemotype and itsessential oil might be a natural potential source for food preservation and for further investigation by developing new bioactive substances.

【 授权许可】

Unknown