Real‐time cardiac metabolism assessed with hyperpolarized [1‐13C]acetate in a large‐animal model

Contrast Media & Molecular Imaging

Matteo Liserani¹  Luigi Landini²  Jan Henrik Ardenkjaer‐³  Fabio A. Recchia³  Giovanni Donato Aquaro³  Giulio Giovannetti³  Francesca Frijia³  Larsen⁴  Vincenzo Lionetti⁴  Alessandra Flori⁵  Maria Filomena Santarelli⁵  Valentina Casieri⁵  Vincenzo Positano⁵ 

[1] Department of Physics University of Pisa Pisa Italy;Department of Physiology Temple University School of Medicine Philadelphia PA USA;Fondazione CNR/Regione Toscana G. Monasterio Pisa Italy;Institute of Clinical Physiology National Council of Research Pisa Italy;Institute of Life Sciences Scuola Superiore Sant'Anna Pisa Italy

关键词: hyperpolarization;    dynamic nuclear polarization (DNP);    magnetic resonance spectroscopy (MRS);    free fatty acid (FA) metabolism;    trityl radical;    [1‐;    13C]acetyl‐;    carnitine;    [1‐;    13C]acetate;    heart metabolism;   

DOI  :  10.1002/cmmi.1618

学科分类：放射科、核医学、医学影像

来源: Hindawi Publishing Corporation

【 授权许可】

CC BY