Chemical composition and biological activities of essential oils and solvent extracts of Origanum vulgare subsp. glandulosum Desf. from Tunisia

Dynamic Chiropractic

Abdennacer Boulila¹  Afef Bejaoui²  Mohamed Boussaid³ 

[1] Laboratory of Natural Substances, National Institute of Research and Physico-chemical Analysis, Technical Pole of Sidi Thabet, 2020, Ariana, Laboratory of Plant Biotechnology, Department of Biology, National Institute of Applied Science and Technology, Centre Urbain Nord, B.P. 676, 1080 Tunis Cedex, Tunisia.;Tunisia.

关键词: Origanum vulgaresubsp.glandulosum;    essential oil;    solvent extract;    biological activities.;   

DOI  :  10.5897/JMPR2013.5043

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

This study aimed to quantify the active biological compounds inOriganum vulgaresubsp.glandulosumDesf. Analysis of the chemical composition essential oil from Tunisia was carried out using gas chromatography-mass spectral (GC-MS). The antioxidant capacities of essential oil and extracts were evaluated using free radical scavenging, ferric reducing antioxidant power assay and metal chelating effects. The antidiabetic activity was screened using α-amylase. The oil was dominated by carvacrol (61.20 to 74.03), p-cymene (5.89 to 12.60), andg-terpinene (1.13 to 6.88). 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing antioxidant power assay (FRAP) assays showed that leaves ofO. vulgarehave a potent antioxidant activities which was comparable to Trolox. The methanol extract have the highest ion chelating ability at around 76.98 mg equivalent ethylenediaminetetraacetic acid (EDTA)/g dry matter (DM).The amounts of chlorophylls A and B were higher than that of lycopene and β-carotene. Essential oils and extracts, screened for α-amylase inhibitory effect, showed a strong capacity to inhibit the degradation of starch by pancreatic and salivary α-amylase. Extracts and essential oils ofO. vulgareshowed substantial antioxidant activity, and detectible inhibitory effect on α-amylase activity, therefore it could be used as a natural preservative ingredient in food and/or pharmaceutical industries.

【 授权许可】

Unknown