In vitro antimicrobial investigation of Zanthoxylum chalybeum stem bark

Dynamic Chiropractic

Institut de Recherche Scientifique et Technologique/Centre de Recherche en Phytomedicaments et Sciences de la Vie/Departement des Phytomedicaments et de Medecine Traditionnelle³  a.⁴  a/Faculte des Sciences⁵  B.P:Butare⁶  a.Universite Nationale du Rw⁷  Rw⁸ 

[1] Nationale du Rwanda/Facultédes Sciences, B.P: 117 Butare, Rwanda.;Institut de Recherche Scientifique et Technologique/Centre de Recherche en PhytoméUniversitédecine Traditionnelle, B.P: 227 Butare, Rwanda.;dicaments et Sciences de la Vie/Dédicaments et de Mépartement des Phytomé

关键词: Zathoxylum chalybeum;    antimicrobial activity;    crude extracts.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The antibacterial properties of ethanolic, dichloromethane (DCM) and acetone ofZanthoxylum chalybeumstem bark were evaluated with the gram negative bacteria (Escherichia coli,Salmonella typhi,Pseudomonas aeruginosa) and gram-positive bacteria (Staphylococcus aureus) andCandida albicans. All tested bacteria have been shown to be resistant to the acetone extracts whereas, onlyS. aureusgrowth has been inhibited by DCM extract (14 mm). Moreover, theethanolic extract inhibited growth ofS. typhi,(17 mm)P.aeruginosa(23 mm)S. aureus(16 mm) around agar well. However,E. coliandC. albicanshave not been inhibited byethanolic extract. For minimum inhibitory concentrations (MICs) determination, acetone extract has no activity against all microorganisms tested whereas both ethanol and DCM exhibited strong activity to theS. aureusat 32 µg/ml of MIC value. The ethanol extract has exhibited low activity againstS. typhi,andP.aeruginosawith respectively 250 and 500 µg/ml of MIC values.

【 授权许可】

Unknown