Surveillance of Severe Acute Respiratory Infection (SARI) for Hospitalized Patients in Northern Vietnam, 2011–2014

Japanese journal of infectious diseases

Loan thi Thanh Tran¹  Mai Quynh Le²  Phuong Mai Vu Hoang²  Son Vu Nguyen²  Hang Khanh Le Nguyen²  Huong Thu Hoang²  Thach Co Nguyen²  Anh Phuong Nguyen²  Thanh Thi Le²  Cuong Duc Vuong² 

[1] National Traditional Medicine Hospital;Virology Department, National Institute of Hygiene and Epidemiology

关键词: respiratory viruses;    severe acute respiratory infection (SARI);    hospitalized patients;    northern Vietnam;   

DOI  :  10.7883/yoken.JJID.2016.463

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

Severe acute respiratory infections (SARI) are leading causes of hospitalization, morbidity, and mortality in children worldwide. The aim of this study was to identify viral pathogens responsible for SARI in northern Vietnam in the period from 2011 to 2014. Throat swabs and tracheal aspirates were collected from SARI patients according to WHO guidelines. The presence of 13 different viral pathogens (influenza A[H1N1]pdm09; A/H3N2; A/H5; A/H7 and B; para influenza 1,2,3; RSV; HMPV; adeno; severe acute respiratory syndrome-CoV and rhino) was tested by conventional/real-time reverse transcription-polymerase chain reaction. During the study period, 975 samples were collected and tested. More than 30% (32.1%, 313 samples) of the samples showed evidence of infection with influenza viruses, including A/H3N2 (48 samples), A (H1N1) pdm09 (221 samples), influenza B (42 samples), and co-infection of A (H1N1) pdm09 or A/H3N2 and influenza B (2 samples). Other respiratory pathogens were detected in 101 samples, including rhinovirus (73 samples), adenovirus (10 samples), hMPV (9 samples), parainfluenza 3 (5 samples), parainfluenza 2 (3 samples), and RSV (1 sample). Influenza A/H5, A/H7, or SARS-CoV were not detected. Respiratory viral infection, particularly infection of influenza and rhinoviruses, were associated with high rates of SARI hospitalization, and future studies correlating the clinical aspects are needed to design interventions, including targeted vaccination.

【 授权许可】

Unknown