Silymarin content in Silybum marianum fruits at different maturity stages

Dynamic Chiropractic

Ahlam Elwekeel¹  Ahlam Elfishawy² 

[1] Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62111, Egypt.;Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

关键词: Silybum marianum;    silymarin;    flavonolignans;    fruits;    maturity;    high performance liquid chromatography (HPLC).;   

DOI  :  10.5897/JMPR12.0743

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Silymarin is one of the most investigated plant extracts with known mechanism of action. It is used for oral treatment of toxic liver damage. Silybin, isosilybin, silychristin and silydianin are the main flavonolignan components of silymarin isolated from the fruits ofSilybum marianum. A reversed-phase high-performance liquid chromatography (HPLC) method for determination of flavonolignans was developed. The method depended on an isocratic solvent system comprising acetonitrile and water containing 0.5% (v/v) phosphoric acid. The method was used for analysis of the flavonolignans content in the fruits ofS.marianumat different maturity stages. A correlation between fruits color, maturity stage and silymarin content is demonstrated.

【 授权许可】

Unknown