Optimization of the extraction of flavonoids from clovers by response surface methodology (RSM)

Dynamic Chiropractic

Fengxia Han¹  Chungang Chen² 

[1] School of Animal Science, Henan Institute of Science and Technology, Xinxiang 453003, China.;School of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.

关键词: Clover;    extraction;    response surface methodology (RSM);    flavonoid.;   

DOI  :  10.5897/JMPR12.1199

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The extraction of flavonoids from clovers (Trifolium) was optimized to maximize flavonoid yield in this study. A central composite design of response surface methodology involving extracting time, liquid-solid ratio, extracting temperature, and ethanol concentration was used, and second-order model for flavonoid yield was employed to generate the response surfaces. The optimum condition for flavonoid yield was determined as follows: 24 min extracting time, 20 liquid-solid ratio, 80°C extracting temperature, and 72% ethanol concentration. Under the optimum condition, the flavonoid yield was 2.29%.

【 授权许可】

Unknown