Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis

Journal of Nepal Paediatric Society

Soumya Roy¹  Subroto Chakrabartty¹ 

[1] Institute Of Child Health, Kolkata

关键词: Macrophage activation syndrome;    Methotrexate;    Systemic Onset Juvenile Idiopathic Arthritis;   

DOI  :  10.3126/jnps.v37i1.16894

学科分类：儿科学

来源: Nepal Paediatric Society

【 摘 要 】

A four year old girl with systemic onset juvenile idiopathic arthritis (SOJIA) developed macrophage activation syndrome (MAS) shortly after starting methotrexate. We observed methotrexate is a likely trigger of MAS in SOJIA. Possibly, there are only two case reports suggesting methotrexate triggered MAS. We reviewed the literature for possible mechanisms.

【 授权许可】

Unknown