期刊论文详细信息
Multiple Sclerosis Journal – Experimental, Translational and Clinical
Cognitive and neuropsychiatric disorders among MS patients from Latin America:
Sandra Vanotti1 
[1]Multiple Sclerosis Clinic, INEBA – Neurosciences Institute of Buenos Aires, Argentina
关键词: Cognition;    neuropsychiatric disorders;    multiple sclerosis;    Latin America;    BICAMS;    cognitive assessment;   
DOI  :  10.1177/2055217317717508
学科分类:医学(综合)
来源: Sage Journals
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【 摘 要 】
Cognitive and neuropsychiatric disorders in patients with multiple sclerosis have been extensively documented. The focus of this review will be on cognitive and neuropsychiatric disorders in multiple sclerosis patients from Latin America, in the context of international literature. Multicentre studies carried out in Latin America have shown that 43% of the patients have cognitive impairment and 34.5% in early stages of the disease, 29% depression and 20.9% neuropsychiatric disorders. The profile of cognitive impairment corresponds to alterations in visual and verbal memory, in attention, in information processing speed and in verbal fluency. The neuropsychiatric profile showed disorders in anxiety, depression, apathy and irritability domains. In the region, there exist validations of the multiple sclerosis neuropsychological screening questionnaire (MSNQ), the brief repeatable battery of neuropsychological tests (BRB-N) and the brief international cognitive assessment for multiple sclerosis (BICAMS), as well as of the paced auditory serial addition test (PASAT) and the symbol digit modalities test (SDMT). A study showed that 53% of the patients who met the NEDA3 condition had cognitive impairment. This finding highlights the need for taking cognitive assessment into account when determining therapeutic efficacy.
【 授权许可】

CC BY-NC   

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