Antioxidant potential and content of phenolic compounds in ethanolic extracts of selected parts of Andrographis paniculata

Dynamic Chiropractic

Koshy Philip¹  Arash Rafat² 

[1]Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

[2]Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.

关键词: Andrographis paniculata;    erythrocytes hemolysis;    superoxide dismutase;    radical scavenging;    phenolic content.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The present study investigated the antioxidant capacity and total content of phenolic compounds in an ethanolic extract of leaves, stems and fruits ofAndrographis paniculata, a medicinal plant. The antioxidant activity of the samples was evaluated by the red cell hemolysis assay, free radical scavenging and superoxide dismutase activities. The Folin–Ciocalteu reagent assay was used to estimate the phenolic content of extracts. Leaf extracts showed the highest antioxidant potential followed by stem and fruit extracts with the rabbit erythrocytes hemolysis and superoxide dismutase activity assays. However,A.paniculatafruit extracts exhibited the highest DPPH free radical scavenging activity compared to the other extracts. A positive correlation between free radical scavenging capacity and the content of phenolic compounds was found in the fruit, leaf and stem extracts of this plant.

【 授权许可】

Unknown