The pH sensitivity of –NH exchange in LnDOTA–tetraamide complexes varies with amide substituent

Contrast Media & Molecular Imaging

Yunkou Wu¹  Garry Kiefer¹  Piyu Zhao²  A. Dean Sherry²  Ana Christina L. Opina² 

[1] 0688 USA;Department of Chemistry University of Texas at Dallas 800 W. Campbell Road Richardson TX 75083‐Macrocyclics 1309 Record Crossing Dallas TX 75235 USA

关键词: MRI;    contrast agents;    pH‐;    responsive agents;    paramagnetic agents;    chemical exchange saturation transfer (CEST) agents;    amide proton exchange;    ratiometric analysis;   

DOI  :  10.1002/cmmi.445

学科分类：放射科、核医学、医学影像

来源: Hindawi Publishing Corporation

【 授权许可】

CC BY