Study of the ventral prostate of Wistar rats treated with Heteropterys tomentosa (A. Juss.)

Dynamic Chiropractic

Juliana Castro Monteiro¹  Karine Moura de Freitas²  Heidi Dolder³  Sebastiatilde⁴  o Roberto Taboga⁶  Marcos de Lucca Moreira Gomes⁶ 

[1] Department of Agrarian and Biological Sciences, Federal University of EspíDepartment of Anatomy, Cell Biology, Physiology and Biophysics, Institute of Biology, State University of Campinas, UNICAMP, Brazil.;Department of Biology, Institute of Biosciences, Language and Science, State University of SãDepartment of Health Sciences, Federal University of Espío Paulo, UNESP, Brazil.;rito Santo, CEUNES, Brazil.

关键词: Aphrodisiac;    Heteropterys aphrodisiaca;    medicinal plants;    phytotherapy;    reproduction.;   

DOI  :  10.5897/JMPR12.421

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Heteropterys tomentosais a Brazilian plant traditionally used as an aphrodisiac and stimulant. Previous studies suggested possible androgenic and antioxidant effects after long term administration ofH. tomentosainfusion. The aim of the present study was to evaluate the effects of this plant infusion on the rat ventral prostate: an androgen responsive organ. Wistar rats were treated, by gavage, withH. tomentosaroots infusion (treated group, n=6) or water (control group, n=6) for 56 days. Morphological, morphometrical and stereological analyses were employed to study the ventral prostate tissue, as well as androgen receptor and apoptotic cell staining. The ultrastructure of the prostatic epithelium was also analyzed. No alteration was observed in the stereological and morphometrical analyses. The pattern of androgen receptor expression and the apoptotic index were identical in the control and treated group. Ultrastructural analysis showed no alterations caused byH. tomentosa. These results suggested that treatment withH. tomentosainfusion, although considered a strong aphrodisiac, did not cause any major damage nor benefit to the prostate tissue.

【 授权许可】

Unknown