SIMULTANEOUS DETERMINATION OF PIPERACILLIN AND TAZOBACTAM IN THE PHARMACEUTICAL FORMULATION TAZONAM® BY DERIVATIVE SPECTROPHOTOMETRY

Journal of The Chilean Chemical Society

NOVA-RAMÍREZ, FRANCISCA¹  NACARATTE, FALLON¹  TORAL, M. INÉS¹ 

[1] University of Chile, Santiago, Chile

关键词: UV-;    vis derivative spectrophotometry;    Piperacillin;    Tazobactam;    Pharmaceutical formulation.;   

DOI  :  10.4067/S0717-97072012000200028

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

In this paper, a simple and rapid method was developed for the simultaneous determination of Piperacillin (PIP) and Tazobactam (TAZ) by second-order derivative spectrophotometry. Water was selected as a solvent for extraction and determination of both analytes. Further studies of photo-stability and forced degradation for both drugs were also performed.

【 授权许可】

Unknown