Comparative bactericidal activity of various soaps against gram-positive and gram-negative bacteria

Scientific Research and Essays

K. Farzana¹ 

关键词:  ;    Gram-positive;    gram-negative;    minimum inhibitory concentration;    minimum bactericidal concentration.;   

DOI  :  10.5897/SRE11.009

学科分类：社会科学、人文和艺术（综合）

来源: Academic Journals

【 摘 要 】

The aim of this study was to check bactericidal activity of eight market soaps from different manufacturers against gram-positive and gram-negative bacteria. Minimum inhibitory concentration disinfectants were determined by broth dilution method. Minimum bactericidal concentration (MBC) of soaps was determined by agar method. Phenol was used as control to compare its activity with soaps. In the list of soaps, along with the standard (Phenol), safeguard was found with highest efficacy in terms of its minimum inhibitory concentration (MIC 256 µg/mL) againstStaphylococcus aureusandEscherichia coli, whereas Johnson and Johnson baby soap (MIC1024 µg/mL) had highest activity againstSalmonella typhi.S. typhihad decreasing sensitivity against various soaps in order as: Johnson and Johnson>Dettol>Safeguard>Phenol>Lifebuoy Red>Lux>Lifebuoy white>Sunlite with MICs values of 1024, 2048, 3072, 6144, 6144, 8192, 12288, 12288 and 16384 µg/mL, respectively.S. aureushad increasing resistance against various soaps as: SafeguardJohnson and Johnson>Lifebuoy red>Lux>Sufi>Sunlite>Lifebuoy white>Phenol>Dettol soap (MICs 256, 256, 2048, 2048, 3072, 4096, 6144, 8192 and 9216 µg/mL, respectively). The MBC values were found to be two to three times greater than its MIC values. The results confirm that medicinal soaps have a greater effect on inhibition and removal of bacterial population than plain soaps.

【 授权许可】

CC BY