In-vitro anti-bacterial activities of crude n-hexane extracts of Garcinia kola (Heckel) seeds against some Vibrio bacteria isolated from wastewater effluents

Scientific Research and Essays

Okoh AI¹ 

关键词:  ;    n-hexane extract;     ;    Garcinia kola;     ;    Vibrio ;    species;    minimum inhibitory concentrations;    rate of kill.;   

DOI  :  10.5897/SRE11.1025

学科分类：社会科学、人文和艺术（综合）

来源: Academic Journals

【 摘 要 】

Crude n-hexane extracts of the seed ofGarcinia kolawere screened for theirin-vitroanti-Vibrioactivities against 50Vibriobacteria isolated from wastewater final effluents in the Eastern Cape Province of South Africa. The extract at a screening concentration of 10 mg/ml resulted in zones of inhibition ranging from 10 to 14 mm against the susceptible isolates and the minimum inhibitory concentrations (MIC) varied between 0.313 and 0.625 mg/ml. The rate of kill assay was done against 3 representative isolates namelyVibrio vulnificus(AL042),Vibrio parahaemolyticus(AL049) andVibrio fluvialis(AL040). The results showed appreciable biocidal activity after 2 h exposure time at 4 × MIC withV. vulnificus(AL042) having 91.6% bacteria cells killed;V. parahaemolyticus(AL049) had 92.6% cells killed andV. fluvialis(AL040) had 96.3% killed. We conclude thatG. kolaseeds are a potential source of compounds that could be useful in the treatment of infections caused byVibriobacteria.

【 授权许可】

CC BY