Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio

PLoS Pathogens

Shahid Khan¹  Maria M. Mota²  Miguel Prudêncio³  Gunnar R. Mair³  Chris Janse³  Carina S. S. Gomes-Santos⁴  Céline Carret⁴  Ana Rita Gomes⁵  Arnab Pain⁵  Andrew Waters⁶  Theresa Feltwell⁶  Joanna Braks⁷ 

[1] Computational Bioscience Research Center (CBRC), Chemical Life Sciencesand Engineering Division, King Abdullah University of Science and Technology(KAUST), Thuwal, Kingdom of Saudi Arabia;Division of Infection and Immunity, Institute of Biomedical Life Sciencesand Wellcome Centre for Molecular Parasitology, Glasgow Biomedical ResearchCentre, University of Glasgow, Glasgow, Scotland;Leiden Malaria Research Group, Parasitology, Leiden University MedicalCentre, Leiden, The Netherlands;Malaria Unit, Instituto de Medicina Molecular, Lisboa,Portugal;Molecular Parasitology Unit, Instituto de Medicina Molecular, Lisbon,Portugal;Pathogen Genetics Group, Wellcome Trust Sanger Institute, Cambridge,United Kingdom;PhD Programme in Experimental Biology and Biomedicine, Center forNeuroscience and Cell Biology, University of Coimbra, Coimbra,Portugal

关键词: Sporozoites;    Parasitic diseases;    Plasmodium;    Salivary gl;    s;    Protein translation;    Blood;    Gametocytes;    Messenger RNA;   

DOI  :  10.1371/journal.ppat.1002046

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

CC BY