Mycobacterium marinum infection: a case report

Journal of venomous animals and toxins

Renata Borges Fortes da Costa Figueira¹  Paula Yoshiko Masuda²  Christiane Salgado Sette³  Fernanda Rodrigues de Oliveira Mattar³  Patrick Alexander Wachholz⁴  Deise Godoy Ura⁴ 

[1] Univ Estadual Paulista, Botucatu, Brazil;Department of Public Health, Botucatu Medical School, UNESP –Instituto Lauro de Souza Lima, Rodovia Comandante João Ribeiro de Barros, Bauru, Brazil

关键词: Mycobacterium infections;    Mycobacterium marinum;    Case report;    Granuloma;   

DOI  :  10.1186/s40409-015-0008-9

学科分类：药理学

来源: BioMed Central

【 摘 要 】

The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.

【 授权许可】

CC BY