In Vivo Bioimaging Rats for Translational Research in Cell and Tissue Transplantation

Cell Medicine

Eiji Kobayashi¹  Takumi Teratani¹ 

[1] Division of Development of Advanced Therapy, Center for Development of Advanced Medical Technology, Jichi Medical University, Shimotsuke-shi, Tochigi, Japan

关键词: Cell transplantation;    Living image;    Translational research;    Transgenic rat;   

DOI  :  10.3727/215517912X639342

学科分类：生物科学（综合）

来源: Cognizant Communication Corporation

【 摘 要 】

The rat is an excellent cell transplantation model. In accordance with the innovative development of in vivo bio-imaging technology, over the last decade we have been developing an engineered rat system based on transgenic technology and have been demonstrating the usefulness of the system with genetically encoded imaging probes such as fluorescent and luminescent proteins. In cooperation with the Japan Society for Organ Preservation and Medical Biology (President: Professor T. Asano), we have also been using luciferase-Tg rats for research into organ preservation and cell transplantation. In this minireview, we introduce the results obtained recently by using these powerful experimental tools during international collaboration in cell transplantation research.

【 授权许可】

CC BY