The Urgent Need for Robust Coral Disease Diagnostics

PLoS Pathogens

David G. Bourne¹  F. Joseph Pollock²  Pamela J. Morris³  Bette L. Willis⁴ 

[1] ARC Centre of Excellence for Coral Reef Studies, School of Marine and Tropical Biology, James Cook University, Townsville, Australia;Australian Institute of Marine Science, Townsville, Australia;Grice Marine Laboratory, College of Charleston, Charleston, South Carolina, United States of America;Hollings Marine Laboratory, Charleston, South Carolina, United States of America

关键词: Corals;    Coral reefs;    Pathogens;    Diagnostic medicine;    Microbial pathogens;    Polymerase chain reaction;    Infectious disease control;    Veterinary diseases;   

DOI  :  10.1371/journal.ppat.1002183

学科分类：生物科学（综合）

来源: Public Library of Science

【 摘 要 】

Coral disease has emerged over recent decades as a significant threat to coral reef ecosystems, with declines in coral cover and diversity of Caribbean reefs providing an example of the potential impacts of disease at regional scales. If similar trends are to be mitigated or avoided on reefs worldwide, a deeper understanding of the factors underlying the origin and spread of coral diseases and the steps that can be taken to prevent, control, or reduce their impacts is required. In recent years, an increased focus on coral microbiology and the application of classic culture techniques and emerging molecular technologies has revealed several coral pathogens that could serve as targets for novel coral disease diagnostic tools. The ability to detect and quantify microbial agents identified as indicators of coral disease will aid in the elucidation of disease causation and facilitate coral disease detection and diagnosis, pathogen monitoring in individuals and ecosystems, and identification of pathogen sources, vectors, and reservoirs. This information will advance the field of coral disease research and contribute knowledge necessary for effective coral reef management. This paper establishes the need for sensitive and specific molecular-based coral pathogen detection, outlines the emerging technologies that could serve as the basis of a new generation of coral disease diagnostic assays, and addresses the unique challenges inherent to the application of these techniques to environmentally derived coral samples.

【 授权许可】

CC BY