Preparation and identification of two new phthalocyanines and study of their anti-cancer activity and anti-bacterial properties

Scientific Research and Essays

Shahriar Ghammamy¹ 

关键词:  ;    Nickel phthalocyanines;    synthesis;    characterization;    biological properties;    anticancer;    anti-bacterial.;   

DOI  :  10.5897/SRE12.365

学科分类：社会科学、人文和艺术（综合）

来源: Academic Journals

【 摘 要 】

Nickel phthalocyanines chloride and nickel phthalocyanines nitrate abbreviated as NiPcCl and NiPc (NO3) respectively were synthesized and characterized. These nickel phthalocyanines are prepared by reaction of phetalic anhydride with urea, ammonium chloride and ammonium heptamolybdate, nickel related salt. Characterization of them was made by microanalyses,Fourier transform infrared spectroscopy (FT-IR)and Ultra violet (UV) visible spectroscopies. The biological properties such as antitumor and antibacterial activities of these compounds were studied. These new compounds showed excellent anti-tumor activity against colon cancer. The anti-bacterial properties of these compounds were studied on Gram-negative and Gram-positive bacterizes, such asEscherichia coli, Pseudomonas aeruginosa, Salmonella, Staphylococcus aureus, Bacillus subtilis.

【 授权许可】

CC BY