COUMARINS OF HAPLOPAPPUS MULTIFOLIUS AND DERIVATIVE AS INHIBITORS OF LOX: EVALUATION IN-VITRO AND DOCKING STUDIES

Journal of The Chilean Chemical Society

FAINI, FRANCESCA¹  TORRES, RENE²  MASCAYANO, CAROLINA²  NÚÑEZ, CAROLINA²  MODAK, BRENDA² 

[1] Universidad de Chile, Chile;Universidad de Santiago de Chile, Chile

关键词: Soybean lipoxygenase;    human lipoxygenase;    coumarin inhibitors of LOX;    percent inhibition values;    docking.;   

DOI  :  10.4067/S0717-97072013000400027

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

Several natural compounds containing a coumarin moiety have been reported. They have multiple biological activities, e.g., as scavengers of reactive oxygen species (ROS) and to reduce the inflammatory processes by inhibition of enzymes like COX or LOX.

【 授权许可】

Unknown