Evaporative light-scattering detector for analysis of natural products

Quimica nova

Rodrigues, Fabiana T.¹  Urano, Raquel P. Morais¹  Berlinck, Roberto G. S.¹ 

[1] Universidade de São Paulo, São Carlos, Brasil

关键词: ELSD;    natural products;    HPLC analysis.;   

DOI  :  10.1590/S0100-40422012000600025

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The interest in the use of evaporative light scattering detector (ELSD) for the analysis of different classes of natural products has grown over the years. This is because this detector has become an excellent alternative compared to other types of detectors, such as the refractive index detector and the ultraviolet (UV) detector. This review describes the basic principles of ELSD functioning and discusses the advantages and disadvantages in using an ELSD for the analysis of organic compounds. Additionaly, an overview, covering the last 23 years, of ELSD applications in natural products analysis (saponins, terpenes, carbohydrates, glycosides, alkaloids, steroids, flavonoids, peptides, polyketides, coumarins and iridoids) is presented and discussed.

【 授权许可】

CC BY