Role of Mean Platelet Volume (MPV) In Diagnosis of Acute Appendicitis

International Journal of Biomedical Research

Divish Saxena¹  B. S. Gedam¹  Mrinal Tandon¹ 

[1] Department of Surgery, NKP Salve Institute of Medical Sciences, Digdoh Hills, Nagpur

关键词: Acute appendicitis;    Mean Platelet Volume;    Platelet sequestration;   

DOI  :  10.7439/ijbr.v6i4.1918

学科分类：基础医学

来源: Scholar Science Journals

【 摘 要 】

The diagnosis of acute appendicitis still remains an enigma for the surgeon. The Mean Platelet volume is known to be a marker determined from megakaryocytes during platelet production, which is associated with platelet function and activation.The mean platelet volume (MPV) decreases in acute inflammatory conditions like acute appendicitis due to increased consumption and sequestration of platelets in the vascular segments of inflamed bowel. In our study of 213 patients, the MPV was determined and was found to be low ( < 7.6fL) in 176 patients ( 82.6%) out of which 175 patients were having features of acute appendicitis on histopathology. Therefore in a patient with a provisional diagnosis of acute appendicitis, a low MPV (<7.6fL) can be taken into consideration along with total leucocyte count with suspected acute appendicitis.

【 授权许可】

CC BY