Designer drugs: analytical and biological aspects

Quimica nova

Chasin, Alice Aparecida da Matta¹  Arbo, Marcelo Dutra²  Thiesen, Flávia Valladão³  Tavares, Rejane⁴  Garcia, Solange Cristina⁵  Limberger, Renata Pereira⁵  Bulcão, Rachel⁵  Baierle, Marília⁵ 

[1] Faculdades Oswaldo Cruz, São Paulo, Brasil;Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre, Brasil;Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brasil;Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brasil;Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil

关键词: biological matrices;    drug abuse;    toxicology.;   

DOI  :  10.1590/S0100-40422012000100027

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and improvement of specific and appropriate analytical methods. This work is a review of the literature which summarizes the characteristics of the drugs and the analytical validated methods using conventional and unconventional matrices currently used for correct identification and quantification of the following classes of emerging drugs of abuse: derivatives of opiates, amphetamines, tryptamines, piperazines and cannabinoids.

【 授权许可】

CC BY