RAPID METHOD OF FRIEDEL-CRAFTS ALKYLATION OF PHLOROGLUCINOL BY MICROWAVE IN DRY MEDIA AND REUSABLE CATALYST

Journal of The Chilean Chemical Society

VERGARA, ALEJANDRA P¹  CONTRERAS, JAVIER A²  OSORIO, MAURICIO E²  CARVAJAL, MARCELA A² 

[1] Centro de Biotecnología DAL, Chile;Universidad Técnica Federico Santa María, Valparaíso, Chile

关键词: Microwave synthesis;    alkylated phloroglucinol;    AgNO3;   

DOI  :  10.4067/S0717-97072015000300020

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

A new rapid and efficient method for the synthesis of a series of alkylated phloroglucinols using conventional microwave is reported 4 phloroglucinol derivatives (4, 5, 6 and 7) were synthesized with good yields (~50%) by a Friedel-Crafts reaction through an Electrophilic Aromatic Substitution mechanism between geraniol/prenol and phloroglucinol, using reusable SiO2 and AgNO3 as the best catalyst tested without solvents under microwave irradiation.

【 授权许可】

Unknown