Is phosphatidylglycerol essential for terrestrial life?

Journal of chemical biology

Samuel Furse¹ 

关键词: Lipid;    Phosphatidylglycerol;    Membrane;    Anionic;    Signal;   

DOI  :  10.1007/s12154-016-0159-3

学科分类：分子生物学，细胞生物学和基因

来源: Springer

【 摘 要 】

Lipids are of increasing importance in understanding biological systems. Lipids carrying an anionic charge are noted in particular for their electrostatic interactions with both proteins and divalent cations. However, the biological, analytical, chemical and biophysical data of such species are rarely considered together, limiting our ability to assess the true role of such lipids in vivo. In this review, evidence from a range of studies about the lipid phosphatidylglycerol is considered. This evidence supports the conclusions that this lipid is ubiquitous in living systems and generally of low abundance but probably fundamental for terrestrial life. Possible reasons for this are discussed and further questions posed.

【 授权许可】

CC BY