Viper bites complicate chronic agrochemical nephropathy in rural Sri Lanka

Journal of venomous animals and toxins

Rivikelum Samarasinghe¹  Niroshana Dahanayake²  Sisira Siribaddana²  Senaka Pilapitiya²  Anjana Silva³ 

[1] Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka;Department of Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka;Department of Parasitology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka

关键词: Snakebite;    Chronic kidney disease;    Agricultural nephropathy;    Epidemiology;    Anuria;   

DOI  :  10.1186/1678-9199-20-33

学科分类：药理学

来源: BioMed Central

【 摘 要 】

Snakebite is a common occupational health hazard among Sri Lankan agricultural workers, particularly in the North Central Province. Viperine snakes, mainly Russell’s viper envenomation, frequently lead to acute renal failure. During the last two decades, an agrochemical nephropathy, a chronic tubulointerstitial disease has rapidly spread over this area leading to high morbidity and mortality. Most of the epidemiological characteristics of these two conditions overlap, increasing the chances of co-occurrence. Herein, we describe four representative cases of viperine snakebites leading to variable clinical presentations, in patients with chronic agrochemical nephropathy, including two patients presented with acute and delayed anuria. These cases suggest the possibility of unusual manifestations of snakebite in patients with Sri Lankan agrochemical nephropathy, of which the clinicians should be aware. It could be postulated that the existing scenario in the Central America could also lead to similar clinical presentations.

【 授权许可】

CC BY