HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR THE QUANTITATIVE ANALYSIS OF CEFUROXIME IN PHARMACEUTICAL PREPARATIONS

Journal of The Chilean Chemical Society

ALAM, SARFARAZ¹  ALI, SAJID¹  RAZA SIDDIQUI, MASOOM²  ALI KHAN, MOONIS²  ALOTHMAN, ZEID A²  MOHAMMAD WABAIDUR, SAIKH² 

[1] Jizan University, Jizan, Saudi Arabia;King Saud University, Riyadh, Saudi Arabia

关键词: Cefuroxime;    High Performance liquid chromatography;    Method validation;    Pharmaceutical preparations;   

DOI  :  10.4067/S0717-97072015000200001

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

New Analytical method has been developed for the determination of Cefuroxime in pharmaceutical formulations. The method involves the application of high performance Liquid chromatography (HPLC) for the quantitative analysis of cefuroxime. HPLC method has a shorter analysis time of 10 min. The developed method obeyed the Beer's law in the range of 5- 300 μg mL-1. Limit of detection (LOD) and limit of quantitation (LOQ) of the developed method was found to be 0.538 and 1.63, μg mL-1 respectively.

【 授权许可】

Unknown