Angiotensin-converting enzyme inhibitors of Bothrops jararaca snake venom affect the structure of mice seminiferous epithelium

Journal of venomous animals and toxins

Joyce M. Gilio¹  Fernanda C. V. Portaro²  Carlos Alberto-Silva³  Antonio C. M. Camargo⁴  Samyr M. Querobino⁵ 

[1] , Brazil;Center for Applied Toxinology, Butantan Institute, SãCenter for Natural and Humanities Sciences (CCNH), Federal University of ABC (UFABC), Santo AndréLaboratory of Immunochemistry, Butantan Institute, São Paulo, Brazil

关键词: B. jararaca;    Bradykinin-potentiating peptides;    Angiotensin-converting enzyme;    Seminiferous epithelium;    Spermatogenesis;   

DOI  :  10.1186/s40409-015-0030-y

学科分类：药理学

来源: BioMed Central

【 摘 要 】

Considering the similarity between the testis-specific isoform of angiotensin-converting enzyme and the C-terminal catalytic domain of somatic ACE as well as the structural and functional variability of its natural inhibitors, known as bradykinin-potentiating peptides (BPPs), the effects of different synthetic peptides, BPP-10c (

【 授权许可】

CC BY